Associate Professor of Chemical Engineering, College of Engineering
NextGen Focus Area: Biomaterials Engineering; Cancer and Immunology
As principal investigator of the Biomodulatory Materials Engineering Laboratory, Bret Ulery leads a team of researchers focused on the design, development and production of novel biomaterials for a variety of biomedical applications primarily in the fields of immunology and regenerative medicine. Inspired by healthy and aberrant biology, Dr. Ulery’s team creates polymer-based products from bioactive molecular building blocks for vaccine development, cancer treatment, immunosuppressive therapies and orthopaedic repair.
Precision Health Impact:
- Developing novel immunomodulatory approaches to prevent infectious diseases, eliminate hematological cancers and facilitate transplant tolerance.
- Creating new products to facilitate bone and nerve repair caused by traumatic and pathological fractures.
Publications:
- Ghavimi SAA, Lungren ES, Stromsdorfer JL, Darkow BT, Nguyen JA, Sun Y, et al. Effect of Dibasic Calcium Phosphate Incorporation on Cellulose Nanocrystal/Chitosan Hydrogel Properties for the Treatment of Vertebral Compression Fractures. AAPS J. 2019 Mar 18;21(3):41.
- Zhang R, Morton LD, Smith JD, Gallazzi F, White TA, Ulery BD. Instructive Design of Triblock Peptide Amphiphiles for Structurally Complex Micelle Fabrication. ACS Biomater Sci Eng. 2018 Jul 9;4(7):2330–9.
- Zhang R, Smith JD, Allen BN, Kramer JS, Schauflinger M, Ulery BD. Peptide Amphiphile Micelle Vaccine Size and Charge Influence the Host Antibody Response. ACS Biomater Sci Eng. 2018 Jul 9;4(7):2463–72.
- Smith JD, Cardwell LN, Porciani D, Nolla A, Cornelison BT, Schulte MC, et al. Therapeutic peptide delivery via aptamer-displaying, disulfide-linked peptide amphiphile micelles. Mol Syst Des Eng. 2020 Jan 20;5(1):269–83.
- Wang X, Zhang R, Lindaman BD, Leeper CN, Schrum AG, Ulery BD. Vasoactive Intestinal Peptide Amphiphile Micelle Chemical Structure and Hydrophobic Domain Influence Immunomodulatory Potentiation. ACS Appl Bio Mater. 2022 Apr 18;5(4):1464–75.
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Biomodulatory Materials Engineering Laboratory
Email: uleryb@umsystem.edu
Department website: https://engineering.missouri.edu/faculty/bret-ulery/