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Diana Gil Pagés, PhD

Diana Gil Pages

Associate Professor of Surgery, Molecular Microbiology and Immunology, School of Medicine
Associate Professor of Biological and Biomedical Engineering, College of Engineering

NextGen Focus Area: Cancer and Immunology

Diana Gil Pagés investigates how antigen recognition by T-cell receptors (TCRs) turns on cell adaptive immune function. Specifically, she is focused on the TCR-associated CD3 multiprotein complex and is the principal discoverer of the CD3 conformational change (CD3Dc), which is at the foundation of her ongoing research. She is studying various levels of control exercised over CD3Dc, including structural, biochemical, developmental and physiological aspects.

Precision Health Impact:

  • Development of novel cancer immunotherapies targeting T cells.  
  • Clinical translation of cancer immunotherapies.  


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