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Haval Shirwan, PhD

Shirwan Headshot

Professor of Child Health, School of Medicine
Professor of Molecular Microbiology and Immunology, School of Medicine

NextGen Focus Area: Cancer

The primary focus of Dr. Shirwan’s translational research program is to develop safe and practical approaches to modulate the immune system for the treatment of immune-based disorders. He co-pioneered with his colleague Esma S. Yolcu, PhD, a proprietary platform known as ProtExTM that allows for the generation of novel recombinant immune ligands and their positional display on biological surfaces as a practical and safe alternative to gene therapy for localized immunomodulation with application to transplantation, autoimmunity, cancer, and infections. 

Precision Health Impact:

  • Using precision medicine to identify immune pathways with druggable targets for the prevention and treatment of cancer, type 1 diabetes, and transplant rejection 
  • Generate novel biologics to druggable immune pathways and employ different vehicles, such as live bacteria and nanoparticles, for their targeted delivery to ensure efficacy and safety 

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