Associate Professor of Molecular Microbiology and Immunology, School of Medicine
NextGen Focus Area: Cancer and Immunology
A healthy individual can mount an immune response to pathogens and tumors while avoiding an autoimmune attack on normal tissues. Mark Daniels studies how signal transduction pathways regulate lymphocyte development, activation and tolerance.
Precision Health Impact:
- Developing and improving therapies for cancer and infectious disease.
- Investigating lymphocyte signaling, oncology and cell biology.
Publications:
- Knudson, KM, Pritzl CJ, Saxena V, Altman, A, Daniels MA, and Teixeiro,E. NFκB–Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality. PNAS Early Edition doi: 10.1073/pnas.1608448114.
- Goplen, N.P., Saxena, V., Knudson, K.M., Schrum, A.G., Gil, D., Daniels, MA., Zamoyska, R., and Teixeiro, E. IL-12 Signals through the TCR To Support CD8 Innate Immune Responses. J Immunol 197, 2434-2443.
- Cunningham, C.A., Cardwell, L.N., Guan, Y., Teixeiro, E., and Daniels, MA. POSH Regulates CD4+ T Cell Differentiation and Survival. Journal of immunology 196, 4003-4013.
- Cunningham CA, Teixeiro E, Daniels MA. 2016. In Vitro Analysis of Thymocyte Signaling. Methods Mol Biol. 2016;1323:169-78. doi: 10.1007/978-1-4939-2809-5_15. PMID: 26294408.
- Cunningham CA, Teixeiro E, Daniels MA. 2016. FTOC-Based Analysis of Negative Selection. Methods Mol Biol. 2016;1323:141-9. doi: 10.1007/978-1-4939-2809-5_12.PMID: 26294405.
Google Scholar
PubMed
ResearchGate
Email: danielsma@missouri.edu
Department website: https://medicine.missouri.edu/faculty/mark-daniels-phd