The goal of the NextGen Cardiovascular, Muscle & Metabolism Science Seminar is to highlight transdisciplinary precision research taking place in cardiovascular, muscle and metabolism fields; provide opportunities for collaboration among researchers to build their own research efforts; and promote clinical/researcher activity across the University of Missouri System and our partners.

For questions about this event, please reach out to Mackenzie Lynch.

"Exploring the Role of MYC in Skeletal Muscle"

Speaker: Kevin A. Murach, PhD
Assistant Professor, Department of Health, Human Performance and Recreation
College of Education and Health Professions
University of Arkansas

Date: Monday, Feb. 10, 2025, 12:00 p.m. - 1:00 p.m.

Location: Tom and Linda Atkins Family Seminar Room, Roy Blunt NextGen Precision Health building

*Zoom option available 

 Register Here

Description

The Oncogene and Yamanaka Factor MYC is strongly induced by exercise in skeletal muscle, but very little is known about its function. This talk will explore the evidence from mice in humans on how MYC can influence skeletal muscle exercise adaptation. I will specifically focus on work from my lab involving a novel genetically modified mouse model, a time course of human muscle samples after exercise, and omics responses.

About the Speaker

Dr. Murach received a PhD in Human Bioenergetics from Ball State University in 2015 and post-doctoral training in muscle stem cell biology at the University of Kentucky Center for Muscle Biology. His research broadly pertains to adult skeletal muscle mass regulation in the context of exercise, aging, and beyond. Dr. Murach uses human muscle samples, conditional and inducible genetic mouse models, cell culture approaches, and advanced single cell/nucleus techniques to address his research questions. He was the recipient of a Ruth L. Kirchstein F32 post-doctoral training award and a K99/R00 Pathway to Independence Award from the National Institutes of Health, is an Editorial Board Fellow at the Journal of Physiology, and his work has been featured in The Scientist, Discover, Men’s Health, and Runner’s World magazines.